This book constitutes the refereed proceedings of the 28th International Conference on Applications of Natural Language to Information Systems, NLDB 2023, held in Derby, UK, in June 21–23, 2023 The 31 full papers and 14 short papers included in this book were carefully reviewed and selected from 89 submissions. They focus on the developments of the application of natural language to databases and information systems in the wider meaning of the term.